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What are the most effective medications for dealling with Acid reflux and GERD? |
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A number of drugs are registered for the treatment of GERD, and they are among the most-often-prescribed forms of medication in most Western countries. They can be used in combination with other drugs, although some antacids can impede the function of other medications:- Antacids before meals or symptomatically after symptoms begin can reduce gastric acidity (increase the pH). Alginic acid may coat the mucosa as well as increase the pH and decrease reflux.
- Gastric H2 receptor blockers such as ranitidine or famotidine can reduce gastric secretion of acid. These drugs are technically antihistamines. They relieve complaints in about 50% of all GERD patients.
- Proton pump inhibitors such as omeprazole are the most effective in reducing gastric acid secretion, as they stop the secretion of acid at the source of acid production, i.e. the proton pump. To maximize effectiveness of this medication the drug should be taken a half hour before meals.
- Prokinetics strengthen the LES and speed up gastric emptying. Cisapride, a member of this class, was withdrawn from the market for causing Long QT syndrome.
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